Books about skin diseases Books about the skin Dermatology Made Easy book. DermNet NZ does not provide an online consultation service. If you have any concerns with your skin or its treatment, see a dermatologist for advice. Discoid lupus erythematosus — codes and concepts open. Chronic cutaneous lupus erythematosus, DLE. Immune disorder. J Invest Dermatol. Clinical outcome measures for cutaneous lupus erythematosus. Determining risk factors for developing systemic lupus erythematosus in patients with discoid lupus erythematosus.
Br J Dermatol. Time to progression from discoid lupus erythematosus to systemic lupus erythematosus: a retrospective cohort study. Clin Exp Dermatol. Characteristics and alternative treatment outcomes of antimalarial-refractory cutaneous lupus erythematosus.
JAMA Dermatol. Cutaneous lupus erythematosus: an update. Indian Dermatol Online J. Drugs for discoid lupus erythematosus. Cochrane Database Syst Rev.
Cutaneous lupus erythematosus: diagnosis and treatment. Best Pract Res Clin Rheumatol. A skin biopsy is usually obtained to diagnose skin lupus, and each form possesses its own characteristic lesions and pattern. Certain drugs can actually cause lupus-like symptoms in people who do not have SLE. However, this form of lupus is temporary and usually subsides within months of the time that the medication is stopped.
In addition, many drugs that cause this form of lupus are actually losing favor among physicians. Medications known to induce lupus-like symptoms in some individuals include the blood pressure medications hydralazine and methyldopa, a heart medication called procainamide, and a drug called D-penicillamine, which is used in cases of metal poisoning.
Other causes of drug-induced lupus include minocycline used to treat acne and anti-TNF used to treat rheumatoid arthritis. A certain form of lupus known as neonatal lupus may affect the babies of women with certain autoantibodies, namely anti-Ro, anti-La, and anti-RNP. About 1 in perfectly healthy women possesses either anti-Ro or anti-La, and a mother who gives birth to a child with neonatal lupus may not have lupus herself. This can be treated by the implantation of a pacemaker, and generally these children go on to lead healthy lives.
Lupus erythematosus LE diseases fall on a spectrum—discoid lupus is at one end and systemic lupus is at the other. Although discoid lupus is more benign than systemic lupus, skin symptoms tend to be more severe in DLE.
In SLE, a malar rash in a butterfly pattern may appear across the nose and cheeks of the patients, or red rashes may develop in reaction to sunlight. It's possible for discoid lupus to spread to your internal organs, although this is rare.
Once the disease moves to internal organs, it becomes SLE. If you have discoid lupus, you will need to routinely check in with your healthcare provider to make sure only your skin is involved. If your healthcare provider suspects you have systemic lupus, they will first run blood tests. If that's ruled out, a skin biopsy may be used to diagnose discoid lupus. When discoid lupus is treated early and effectively, skin lesions can clear up completely.
Without effective treatment, permanent scarring may result. Discoid lupus may be treated with topical corticosteroids, such as cortisone ointment; topical calcineurin inhibitors, like pimecrolimus cream or tacrolimus ointment; and corticosteroid cortisone injections. If topical treatments don't work for you and your lesions are too widespread for corticosteroid injections , you may be prescribed antimalarial tablets such as hydroxychloroquine, chloroquine, and quinacrine.
Taking these antimalarials can cause vision problems, so you'll need a baseline eye exam and periodic eye exams going forward. In rare cases, when none of these approaches work, your healthcare provider may suggest more aggressive medications, such as methotrexate, acitretin, isotretinoin, mycophenolate mofetil, or dapsone.
If you've been diagnosed with discoid lupus, you'll also need to avoid sun exposure, wear hats and sun-protective clothing, and use a broad-spectrum sunscreen with an SPF higher than Smoking is also associated with discoid lupus, so quitting smoking should be a priority for you. Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life.
Genetic similarities and differences between discoid and systemic lupus erythematosus patients within the Polish population. Postepy Dermatol Alergol. Provost TT. Archives of Dermatology. Your Privacy Rights. To change or withdraw your consent choices for VerywellHealth.
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