While some 47,XYY individuals are infertile, those who are able to reproduce often produce offspring that have normal karyotypes. Excerpt Jacobs syndrome, also known as 47,XYY syndrome, is a rare genetic condition that occurs in about 1 out of male children. Publication types Review. Contact a health care provider if you have questions about your health. From Genetics Home Reference.
Description 47,XYY syndrome is characterized by an extra copy of the Y chromosome in each of a male's cells. Frequency This condition occurs in about 1 in 1, newborn boys. Causes People normally have 46 chromosomes in each cell. Learn more about the chromosome associated with 47,XYY syndrome y chromosome. Inheritance Most cases of 47,XYY syndrome are not inherited.
Research Studies from ClinicalTrials. J Pediatr. Epub Jun The XYY syndrome: a follow-up study on 38 boys. Genet Couns. Early manifestations in a cohort of children prenatally diagnosed with 47,XYY. To diagnosis XYY syndrome, doctors check a blood sample for the extra Y chromosome. Before birth, the condition may be found through karyotype test chromosomal analysis or noninvasive prenatal testing NIPT.
NIPT is done on the fluid surrounding the fetus, tissue from the placenta, or the blood from the mother. After birth, doctors can make a diagnosis with a karyotype or with a microarray test from the baby. Finding services early is important and can greatly increase their ability to help boys live a healthier, more productive life.
Options vary greatly depending on how old a boy is at the time of his diagnosis, whether he has noticeable symptoms, and the severity of those symptoms. Regular doctor visits.
At periodic visits, a doctor can monitor a boy's development for delays, social and language disabilities, or health problems and treat these promptly. Educational support services. Educational support can teach boys ways to keep pace in school. Some might be eligible for an individualized educational program IEP or education plan , which are designed to help children with special needs.
Early intervention services. It can be very helpful and often more effective for a boy to have speech , occupational , physical , or developmental therapy in the early months of life or as soon as concerns are found. Speech therapy and physical therapy can improve a boy's speaking, reading, and writing skills and help increase strength and coordination. Occupational therapy and behavioral therapy can help them develop more confidence and interact better with other children.
The whole family can benefit from counseling to better understand XYY syndrome and help a boy who has it to live a productive life. Early inventions should be considered at infancy for physical therapy, at 15 months for speech delay, at 1st grade for reading and learning issues, and at 3rd grade for anxiety or depression. Boys with XYY syndrome can develop speech, learning, or social challenges at a young age. This can make them more likely to have low self-esteem and lead to school or social problems.
If your son has trouble making friends or struggles in school, talk to your doctor or the principal or school counselor.
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